Principal investigator, DR1 – CNRS
pierre(dot)nassoy(at)u-bordeaux(dot)fr
Research interests/keywords
Tissue mechanics
Single cell & multicellular mechanotransduction
Oncophysics
Bio-microfluidics
Optofluidics
Education
PhD in Physical Chemistry – 1996
University of Paris 6
Master 2 (DEA) in Softcondensed Matter Physics – 1992
University of Paris 6
Professional experience
CNRS Senior scientist – 2012-…
Bioimaging and Optofluidics Group, LP2N – UMR 5298
IOGS, CNRS & University of Bordeaux, Talence, FR
CNRS Senior scientist – 2009-2012
PCC – UMR 168
Institut Curie, CNRS & University of Paris 6, Paris, FR
CNRS Junior scientist – 1999-2009
PCC – UMR 168
Institut Curie, CNRS & University of Paris 6, Paris, FR
Post-doctoral scientist – August 1996- January 1999
Dynamic Force Spectroscopy
Department of Physics and Pathology, University of British Columbia, Vancouver, Canada
Advisor: Evan Evans
PhD in Soft Condensed Matter Physics – 1993-1996
Segregation effects in Langmuir films
Institut Curie, Paris, France
Supervisor: Francis Rondelez
10 selected publications
Murrell M.P., Voituriez R., Joanny J-F., Nassoy P.*, Sykes C. and Gardel M.L.. Liposome Adhesion Generates Traction Stress. Nature Physics, 10: 163-169 (2014).
Alessandri K., Sarangi B.R. , Gurchenkov V.V., Sinha B., Kiessling T.R., Fetler L., Rico F., Scheuring S., Lamaze C., Simon A., Geraldo S., Vignjevic D., Domejean H., Rolland L., Funfak A., Bibette J., Bremond N., Nassoy P*. Cellular capsules as a tool for multicellular spheroid production and for investigating the mechanics of tumor progression in vitro. Proc. Natl. Acad. Sci. USA, 110 (37): 14843−14848 (2013).
Sinha B., Köster D., Ruez R., Gonnord P., Bastiani M., Abankwa D., Stan R. V., Butler-Browne G., Vedie B., Johannes L., Morone N., Parton R. G., Raposo G., Sens P., Lamaze C., Nassoy P*. Cells respond to mechanical stress by rapid disassembly of caveolae. Cell, 144: 402-413 (2011).
Mabrouk E., Cuvelier, D., Brochard-Wyart F., Nassoy P.*, Li M.-H. Bursting of sensitive polymersomes induced by curling. Proc. Nat. Acad. Sci. U.S.A. 106: 7294-7298 (2009).
Cuvelier D., Théry M. Chu Y.-S., Dufour S., Thiery J.-P., Bornens M., Nassoy P.*, Mahadevan L. The universal dynamics of cell spreading. Current Biology 17: 694-699 (2007).
Brochard-Wyart F., Borghi N., Cuvelier D., Nassoy P. Hydrodynamic narrowing of tubes extruded from cells. Proc. Nat. Acad. Sci. 103: 7660-7663 (2006).
Cuvelier D., Nassoy P.* Hidden dynamics of vesicle adhesion induced by specific stickers. Phys. Rev. Lett. 93: 228101 (2004).
Perret E., Leung A., Morel A., Feracci H., and Nassoy P.* Versatile decoration of glass surfaces to probe individual protein-protein interactions and cellular adhesion. Langmuir 18: 846-854 (2002).
Merkel R., Nassoy P., Leung A., Ritchie K. and Evans E. Energy landscapes of receptor-ligand bonds explored with dynamic force spectroscopy . Nature 397: 50-53 (1999).
Nassoy P., Birch W. R., Andelman D. and Rondelez F. Hydrodynamic Mapping of Two-Dimensional Electric Fields in Monolayers. Phys. Rev. Lett. 76: 455-458 (1996).