Pierre Nassoy

Principal investigator, DR1 – CNRS



Research interests/keywords

Tissue mechanics

Single cell & multicellular mechanotransduction





PhD in Physical Chemistry – 1996

University of Paris 6


Master 2 (DEA) in Softcondensed Matter Physics – 1992

University of Paris 6

Professional experience

CNRS Senior scientist – 2012-…

Bioimaging and Optofluidics Group, LP2N – UMR 5298

IOGS, CNRS & University of Bordeaux, Talence, FR


CNRS Senior scientist – 2009-2012

PCC – UMR 168

Institut Curie, CNRS & University of Paris 6, Paris, FR


CNRS Junior scientist – 1999-2009

PCC – UMR 168

Institut Curie, CNRS & University of Paris 6, Paris, FR


Post-doctoral  scientist – August 1996- January 1999

Dynamic Force Spectroscopy

Department of Physics and Pathology, University of British Columbia, Vancouver, Canada

Advisor: Evan Evans


PhD in Soft Condensed Matter Physics – 1993-1996

Segregation effects in Langmuir films

Institut Curie, Paris, France

Supervisor: Francis Rondelez

10 selected publications

Murrell M.P., Voituriez R., Joanny J-F., Nassoy P.*, Sykes C. and Gardel M.L.. Liposome Adhesion Generates Traction StressNature Physics, 10: 163-169 (2014).


Alessandri K.,  Sarangi B.R. , Gurchenkov V.V., Sinha B.,  Kiessling T.R., Fetler L., Rico F., Scheuring S., Lamaze C., Simon A., Geraldo S., Vignjevic D., Domejean H., Rolland L., Funfak A., Bibette J., Bremond N., Nassoy P*. Cellular capsules as a tool for multicellular spheroid production and for investigating the mechanics of tumor progression in vitro. Proc. Natl. Acad. Sci. USA, 110 (37): 14843−14848 (2013).


Sinha B., Köster D., Ruez R., Gonnord P., Bastiani M., Abankwa D., Stan R. V., Butler-Browne G., Vedie B., Johannes L., Morone N., Parton R. G., Raposo G., Sens P., Lamaze C., Nassoy P*. Cells respond to mechanical stress by rapid disassembly of caveolaeCell, 144: 402-413 (2011).


Mabrouk E., Cuvelier, D., Brochard-Wyart F., Nassoy P.*, Li M.-H. Bursting of sensitive polymersomes induced by curling. Proc. Nat. Acad. Sci. U.S.A.  106: 7294-7298 (2009).


Cuvelier D., Théry M. Chu Y.-S., Dufour S., Thiery J.-P., Bornens M., Nassoy P.*, Mahadevan L. The universal dynamics of cell spreading. Current Biology 17: 694-699 (2007).


Brochard-Wyart F., Borghi N., Cuvelier D., Nassoy P. Hydrodynamic narrowing of tubes extruded from cells. Proc. Nat. Acad. Sci. 103: 7660-7663 (2006).


Cuvelier D., Nassoy P.* Hidden dynamics of vesicle adhesion induced by specific stickers. Phys. Rev. Lett. 93: 228101 (2004).


Perret E., Leung A., Morel A., Feracci H., and Nassoy P.* Versatile decoration of glass surfaces to probe individual protein-protein interactions and cellular adhesion. Langmuir 18: 846-854 (2002).


Merkel R., Nassoy P., Leung A., Ritchie K. and Evans E. Energy landscapes of receptor-ligand bonds explored with dynamic force spectroscopy . Nature 397: 50-53 (1999).


Nassoy P., Birch W. R., Andelman D. and Rondelez F. Hydrodynamic Mapping of Two-Dimensional Electric Fields in Monolayers. Phys. Rev. Lett. 76: 455-458 (1996).