Gaëlle Recher

Permanent researcher, CRCN – CNRS



Research interests / keywords

Cell self-organisation

Tissue biophysics

Physiomimetic morphogenesis

Microscopies (non linear, light sheet)


Scientific responsabilities

Member of the board of the CNRS GdR ImaBio

Coordination of the workgroup ‘Imaging Multicellular Systems’


PhD in Biology – 2010

University of Rennes 1


Master 2 in Neurosciences (Eq. to MSc) – 2006

Pierre & Marie Curie University, Paris

Previous labs

Postdoctoral scientist – 2015 November-2017 September

BioImaging and OptoFluidics Group, LP2N – UMR 5298
IOGS, CNRS & University of Bordeaux, Talence, FR
Advisor: Pierre Nassoy
Biophysics of cell assembly in confined & controlled environment


Postdoctoral scientist – 2014 May-2015 October

Magdalena Zernicka-Goetz Group
Department of Physiology, Development and Neuroscience & Gurdon Institute, University of Cambridge, UK
Advisor: Magdalena Zernicka-Goetz
Role of intracellular signalling during mouse & human embryo pre- to post-implantation development and establishment of two-photon imaging and 4D analyses of morphogenesis. Isaak Newton Trust Fellowship


Postdoctoral scientist – 2011 January-2014 June

Multiscale Dynamics in Animal Morphogenesis, BioEmergences
FRC2118 CNRS, Alfred Fessard Neurobiology Institute, Gif-sur-Yvette, FR
Advisor: Nadine Peyriéras
Neural progenitors in the zebrafish midbrain investigated with 3D+time two-photon microscopy & Two-photon and light sheet microscopy developments, artificial assistant conception


Research associate – 2010 January-December

Molecular chemistry to molecular photonics laboratory, UMR 6510, University of Rennes, FR
Advisor: Mireille Blanchard-Desce
FEDER European grants. Biological valorization of multichromophoric Bodipies with in vivo multiphoton imaging of xenopus tadpoles


PhD in Biology – 2006 October-2010 July

UMR 6026, CNRS, University of Rennes, FR
Supervisor: François Tiaho; co-supervisor: Pascal Benquet
Two-photon microscopy contribution to striated muscular tissue and nervous system studies


Master 2 (MSc) internship – 2006 January-June

Oheim-Ropert group
U603, Neurophysiology and New Microscopies Laboratory, INSERM, Paris, FR
Supervisor: Nicole Ropert
5-HT diffusion at central synapse: amperometric signal simulation



Andrique, L*, Recher, *, Alessandri, K, Pujol, N, Feyeux, M, Bon, P, Cognet, L, Nassoy, P, and Bikfalvi, A (2019). A model of guided cell self-organization for rapid and spontaneous formation of functional vessels. Science Advances, eaau6562.


Reichhardt, M P, Lundin, K, Lokki, A I, Recher, G, Vuoristo, S, Katayama, S, Tapanainen, J, Kere, J, Meri, S, and Tuuri, T (2019). Complement in human pre-implantation embryos: attack and defense. bioRxiv, 595561.


Shahbazi M, Scialdone A, Skorupska N, Weberling A, Recher G, Zhu M, Jedrusik A, Devito L, Noli L, Macaulay I, Buecker C, Khalaf Y, Ilic D, Voet T, Marioni J, Zernicka-Goetz M (2017) Pluripotent state transitions coordinate morphogenesis in mouse and human embryos. Nature


Hinaux H, Recher G, Alié A, Legendre L, Blin M & Rétaux S (2017) Lens apoptosis in the Astyanax blind cavefish is not triggered by defects in morphogenesis or community effect. PlosOne


Alessandri K*, Andrique L*, Feyeux M*, Bikfalvi A, Nassoy P & Recher G† (2017) All-in-one 3D printed microscopy chamber for multidimensional imaging, the UniverSlide. Scientific Reports


Joly J-S, Recher G, Brombin A, Ngo K & Hartenstein V (2016) Conveyor-belt neurogenesis: a conserved mode of generating a complex, homotopically patterned visual system in insects and vertebrates. Current Biology


Shahbazi M*, Jedrusik A*, Vuoristo S*, Recher G, Hupalowska A, Campbell A, Fishel S & Zernicka-Goetz M (2016) In vitro culture of human embryos reveals self-organization of the epiblast during implantation stages. Nature Cell Biology


Faure E*, Savy T*, Rizzi B*, Melani C*, Stasova O*, Fabrèges D*, Spir R, Hammons M, Cunderlik R, Recher G, Lombardot B, Duloquin L, Colin I, Kollar J, Desnoulez S, Affaticati P, Maury B, Boyreau A, Nief J-Y, Calvat P, Vernier P, Frain M, Lutfalla G, Kergosien Y, Suret P, Remesikova M, Doursat R, Sarti A, Mikula K, Peyriéras N & Bourgine P (2016) An algorithmic workflow for the automated processing of 3D+time microscopy images of developing organisms and the reconstruction of their cell lineage. Nature Communications


Recher G, Coumailleau P, Rouède D & Tiaho F (2015) Structural origin of the drastic modification of second harmonic generation intensity pattern occurring in tail muscles of climax stages xenopus tadpoles. Journal of Structural Biology


Recher G*, Jouralet J*, Brombin A, Heuzé A, Mugniery E, Hermel J-M, Desnoulez S, Savy T, Herbomel P, Bourrat F, Peyriéras N, Jamen F & Joly J-S (2013) Zebrafish midbrain slow-amplifying progenitors exhibit high levels of transcripts for nucleotide and ribosome biogenesis. Development


Rouède D, Bellanger J-J, Recher G & Tiaho F (2013) Study of the effect of myofibrillar misalignment on the sarcomeric SHG intensity pattern. Optics Express


Rouède D, Bellanger J-J, Schaub E, Recher G & Tiaho F (2013) Theoretical and Experimental SHG Angular Intensity Patterns from Healthy and Proteolysed Muscles. Biophysical Journal


Parthasarathy V, Fery-Forgues S, Campioli E, Recher G, Terenziani F & Blanchard-Desce M (2011) Dipolar versus octupolar triphenylamine-based fluorescent organic nanoparticles as brilliant one- and two-photon emitters for (bio)imaging. Small


Rouède D, Recher G, Bellanger J-J, Lavaut M-T, Schaub E & Tiaho F (2011) Modeling of supramolecular centrosymmetry effect on sarcomeric SHG intensity pattern of skeletal muscles. Biophysical Journal


Recher G, Rouède D, Schaub E & Tiaho F (2011) Skeletal muscle sarcomeric SHG patterns photo-conversion by femtosecond infrared laser. Biomedical Optics Express


Recher G, Rouède D, Tascon C, D’Amico LA & Tiaho F (2011) Double-band sarcomeric SHG pattern induced by adult skeletal muscles alteration during myofibrils preparation. Journal of Microscopy


Recher G, Rouède D, Richard P, Simon A, Bellanger J-J & Tiaho F (2009) Three distinct sarcomeric patterns of skeletal muscle revealed by SHG and TPEF Microscopy. Optics Express


L’hostis-Guidet A, Recher G, Guillet B, Al-Mohammad A, Coumailleau P, Tiaho F, Boujard D & Madigou T (2009) Generation of stable Xenopus laevis transgenic lines expressing a transgene controlled by weak promoters. Transgenic Research


Mongin O, Rouxel C, Robin AC, Pla-Quintana A, Krishna TR, Recher G, Tiaho F, Caminade AM, Majoral JP & Blanchard-Desce M (2008) Brilliant organic nanodots: novel nano-objects for bionanophotonics – art. no. 704006. 7040:4006-4006. SPIE Proceedings. Nanobiosystems: Processing, Characterization, and Applications


Tiaho F, Recher G & Rouède D (2007) Estimation of helical angles of myosin and collagen by second harmonic generation imaging microscopy. Optics Express



Andrique L, Recher G, Bikfavli A, Alessandri K, Feyeux M, Nassoy P (2017) Microfibre cellulaire creuse et procédé de fabrication d’une telle microfibre cellulaire creuse. FR 17 5194


Recher G, Alessandri K, Andrique L, Feyeux M, Nassoy P, Bikfavli A (2016) Chambre de culture et d’imagerie d’échantillons biologique. FR 16 63241


Feyeux M, Alessandri K, Recher G, Cognet L, Bezard E, Nassoy P (2016) Microcompartiment cellulaire et procédés de préparation. FR 16 61377